You must comply with the ICO-approved plan and document that compliance in the annual Research Performance Progress Report (RPPR). Non-compliance may result in enforcement action from the NIH such as
Non-compliance may also affect future funding decisions. To avoid possible issues when reporting progress, ensure that your submitted plan contains enough detail for the program officer to be able to evaluate compliance.
If you make changes to your submitted plan, your new plan must be re-approved by NIH. the process varies depending on if the change is made pre-award or post-award.
NIH expects that you will indicate how compliance with the Data Management and Sharing Plan will be monitored and managed.