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Small Animal Internal Medicine Journal Club

2016 - 2017

PubMed Collection of All Articles

04/21/17 Robinson: Posaconazole; Abdominal Lymph Nodes

Corrigan VK, Legendre AM, Wheat LJ, Mullis R, Johnson B, Bemis DA, Cepero L. Treatment of Disseminated Aspergillosis with Posaconazole in 10 Dogs. J Vet Intern Med. 2016 Jan-Feb;30(1):167-73. doi: 10.1111/jvim.13795. Epub 2015 Nov 14.
PubMed PMID: 26566711; PubMed Central PMCID: PMC4913654.

Davé AC, Zekas LJ, Auld DM. Correlation of cytologic and histopathologic findings with perinodal echogenicity of abdominal lymph nodes in dogs and cats.Vet Radiol Ultrasound. 2017 Apr 11. doi: 10.1111/vru.12499. [Epub ahead of print] PubMed PMID: 28397313.

04/14/17 Sprinkle: Nutrition and Renal Disease

Hall JA, Fritsch DA, Yerramilli M, Obare E, Yerramilli M, Jewell DE. A longitudinal study on the acceptance and effects of a therapeutic renal food in pet dogs with IRIS-Stage 1 chronic kidney disease. J Anim Physiol Anim Nutr (Berl). 2017 Mar 9. doi: 10.1111/jpn.12692. [Epub ahead of print] PubMed PMID:28276099. [to be discussed]

WSAVA's Nutrition Toolkit

04/07/07 Shomper: Fly Biting in Dogs

Frank D, Bélanger MC, Bécuwe-Bonnet V, Parent J. Prospective medical evaluation of 7 dogs presented with fly biting. Can Vet J. 2012 Dec;53(12):1279-84. PubMed PMID: 23729825; PubMed Central PMCID: PMC3500118.

Wrzosek M, Płonek M, Nicpoń J, Cizinauskas S, Pakozdy A. Retrospective multicenter evaluation of the "fly-catching syndrome" in 24 dogs: EEG, BAER, MRI, CSF findings and response to antiepileptic and antidepressant treatment. Epilepsy
Behav. 2015 Dec;53:184-9. doi: 10.1016/j.yebeh.2015.10.013. Epub 2015 Nov 13.PubMed PMID: 26584225.

03/31/17 Jurkoshek: Meningomyelitis; Toxoplasma gondii

Griffin JF, Levine JM, Levine GJ, Fosgate GT. Meningomyelitis in dogs: a retrospective review of 28 cases (1999 to 2007). J Small Anim Pract. 2008 Oct;49(10):509-17. doi: 10.1111/j.1748-5827.2008.00588.x. Epub 2008 Jul 8. PubMed
PMID: 18631217.

Wyrosdick HM, Schaefer JJ. Toxoplasma gondii: history and diagnostic test development. Anim Health Res Rev. 2015 Dec;16(2):150-62. doi:10.1017/S1466252315000183. Epub 2015 Nov 16. Review. PubMed PMID: 26568360.

03/24/17 Rippy: CGUC; TCC

Nolan MW, Kogan L, Griffin LR, Custis JT, Harmon JF, Biller BJ, Larue SM. Intensity-modulated and image-guided radiation therapy for treatment of genitourinary carcinomas in dogs. J Vet Intern Med. 2012 Jul-Aug;26(4):987-95.doi: 10.1111/j.1939-1676.2012.00946.x. PubMed PMID: 22624845. (to be discussed)

Fulkerson CM, Knapp DW. Management of transitional cell carcinoma of the urinary bladder in dogs: a review. Vet J. 2015 Aug;205(2):217-25. doi:10.1016/j.tvjl.2015.01.017. Review. PubMed PMID: 25747698. (good for boards prep)

03/17/17 Leach: Inherited Arrhythmias

Gelzer AR, Kraus MS, Rishniw M, Hemsley SA, Moïse NS. Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized
cross-over study. J Vet Cardiol. 2010 Aug;12(2):93-106. doi:10.1016/j.jvc.2010.06.001. PubMed PMID: 20663731.

Moïse NS. Inherited arrhythmias in the dog: potential experimental models of cardiac disease. Cardiovasc Res. 1999 Oct;44(1):37-46. Review. PubMed PMID:10615388.

03/10/17 Cochran: Meningoencephalitis of Unknown Origin

Lowrie M, Thomson S, Smith P, Garosi L. Effect of a constant rate infusion of cytosine arabinoside on mortality in dogs with meningoencephalitis of unknown origin. Vet J. 2016 Jul;213:1-5. doi: 10.1016/j.tvjl.2016.03.026. PubMed PMID:

Cornelis I, Volk HA, Van Ham L, De Decker S. Prognostic factors for 1-week survival in dogs diagnosed with meningoencephalitis of unknown aetiology. Vet J. 2016 Aug;214:91-5. doi: 10.1016/j.tvjl.2016.05.008. PubMed PMID: 27387733.

03/03/17 Grobman: Upper Respiratory Syndrome; Reflux

Poncet CM, Dupre GP, Freiche VG, Bouvy BM. Long-term results of upper respiratory syndrome surgery and gastrointestinal tract medical treatment in 51 brachycephalic dogs. J Small Anim Pract. 2006 Mar;47(3):137-42. PubMed PMID:16512845.

Kook PH, Kempf J, Ruetten M, Reusch CE. Wireless ambulatory esophageal pH monitoring in dogs with clinical signs interpreted as gastroesophageal reflux. J Vet Intern Med. 2014 Nov-Dec;28(6):1716-23. doi: 10.1111/jvim.12461. PubMed PMID:25269696; PubMed Central PMCID: PMC4895632.

02/17/17 Bryan: Lymphoma

Childress MO, Ramos-Vara JA, Ruple A. A randomized controlled trial of the effect of prednisone omission from a multidrug chemotherapy protocol on treatment outcome in dogs with peripheral nodal lymphomas. J Am Vet Med Assoc. 2016 Nov
1;249(9):1067-1078. PubMed PMID: 27767437.

Simon D, Moreno SN, Hirschberger J, Moritz A, Kohn B, Neumann S, Jurina K, Scharvogel S, Schwedes C, Reinacher M, Beyerbach M, Nolte I. Efficacy of a continuous, multiagent chemotherapeutic protocol versus a short-term single-agent protocol in dogs with lymphoma. J Am Vet Med Assoc. 2008 Mar 15;232(6):879-85. doi: 10.2460/javma.232.6.879. PubMed PMID: 18341445.

02/10/17 Coates: Hyperparathyroidism; Hypercalcemia; Hypocalcemia

Arbaugh M, Smeak D, Monnet E. Evaluation of preoperative serum concentrations of ionized calcium and parathyroid hormone as predictors of hypocalcemia following parathyroidectomy in dogs with primary hyperparathyroidism: 17 cases
(2001-2009). J Am Vet Med Assoc. 2012 Jul 15;241(2):233-6. doi:10.2460/javma.241.2.233. PubMed PMID: 22765370.

Milovancev M, Schmiedt CW. Preoperative factors associated with postoperative hypocalcemia in dogs with primary hyperparathyroidism that underwent parathyroidectomy: 62 cases (2004-2009). J Am Vet Med Assoc. 2013 Feb 15;242(4):507-15. doi: 10.2460/javma.242.4.507. PubMed PMID: 23363283.

Shelton GD, Cardinet GH 3rd. Pathophysiologic basis of canine muscle disorders. J Vet Intern Med. 1987 Jan-Mar;1(1):36-44. Review. PubMed PMID:2976093. [Good review article; focus on Figure 4]

de Brito Galvão JF, Schenck PA, Chew DJ. A Quick Reference on Hypercalcemia. Vet Clin North Am Small Anim Pract. 2017 Mar;47(2):241-248. doi:10.1016/j.cvsm.2016.10.016. Review. PubMed PMID: 28012787. [For your files]

de Brito Galvão JF, Schenck PA, Chew DJ. A Quick Reference on Hypocalcemia. Vet Clin North Am Small Anim Pract. 2017 Mar;47(2):249-256. doi:10.1016/j.cvsm.2016.10.017. Review. PubMed PMID: 28012786. [For your files]

02/03/17 Sibigtroth: Polyradiculoneuritis

Hirschvogel K, Jurina K, Steinberg TA, Matiasek LA, Matiasek K, Beltrán E, Fischer A. Clinical course of acute canine polyradiculoneuritis following treatment with human IV immunoglobulin. J Am Anim Hosp Assoc. 2012 Sep-Oct;48(5):299-309. doi: 10.5326/JAAHA-MS-5651. PubMed PMID: 22843822.

Añor S. Acute lower motor neuron tetraparesis. Vet Clin North Am Small Anim Pract. 2014 Nov;44(6):1201-22. doi: 10.1016/j.cvsm.2014.07.010. PubMed PMID:25441630. [For your record]

01/27/17 Vientos-Plotts: Cholecystectomy

Malek S, Sinclair E, Hosgood G, Moens NM, Baily T, Boston SE. Clinical findings and prognostic factors for dogs undergoing cholecystectomy for gallbladder mucocele. Vet Surg. 2013 May;42(4):418-26. doi:10.1111/j.1532-950X.2012.01072.x. PubMed PMID: 23330871.

Kook PH, Schellenberg S, Rentsch KM, Reusch CE, Glaus TM. Effects of iatrogenic hypercortisolism on gallbladder sludge formation and biochemical bile constituents in dogs. Vet J. 2012 Feb;191(2):225-30. doi:10.1016/j.tvjl.2011.01.004. PubMed PMID: 21316991.

01/20/17 Anderson: EBVM

Grimes DA, Schulz KF. An overview of clinical research: the lay of the land. Lancet. 2002 Jan 5;359(9300):57-61. Review. PubMed PMID: 11809203.

01/13/17 Flesner: Immune Thombocytopenia; Common Prostatic Conditions in Dogs

LeVine DN, Birkenheuer AJ, Brooks MB, Nordone SK, Bellinger DA, Jones SL, Fischer TH, Oglesbee SE, Frey K, Brinson NS, Peters AP, Marr HS, Motsinger-Reif A, Gudbrandsdottir S, Bussel JB, Key NS. A novel canine model of immune thrombocytopenia: has immune thrombocytopenia (ITP) gone to the dogs? Br J Haematol. 2014 Oct;167(1):110-20. doi:10.1111/bjh.13005. PubMed PMID: 25039744; PubMed Central PMCID: PMC4167465.

Niżański W, Levy X, Ochota M, Pasikowska J. Pharmacological treatment for common prostatic conditions in dogs - benign prostatic hyperplasia and prostatitis: an update. Reprod Domest Anim. 2014 Jun;49 Suppl 2:8-15. doi:10.1111/rda.12297. Review. PubMed PMID: 24947855.

12/16/16 Menard: Insulinoma; Hypoglycemia in Dogs

Goutal CM, Brugmann BL, Ryan KA. Insulinoma in dogs: a review. J Am Anim Hosp Assoc. 2012 May-Jun;48(3):151-63. doi: 10.5326/JAAHA-MS-5745. Review. PubMed PMID: 22474047.

Datte K, Guillaumin J, Barrett S, Monnig A, Cooper E. Retrospective evaluation of the use of glucagon infusion as adjunctive therapy for hypoglycemia in dogs: 9 cases (2005-2014). J Vet Emerg Crit Care (San Antonio). 2016 Nov;26(6):775-781.
doi: 10.1111/vec.12513. PubMed PMID: 27541206.

12/09/16 Ortolani: Hypoadrenocorticism in Dogs

Gold AJ, Langlois DK, Refsal KR. Evaluation of Basal Serum or Plasma Cortisol Concentrations for the Diagnosis of Hypoadrenocorticism in Dogs. J Vet Intern Med. 2016 Nov;30(6):1798-1805. doi: 10.1111/jvim.14589. PubMed PMID: 27714859; PubMed Central PMCID: PMC5115184.

Gunn E, Shiel RE, Mooney CT. Hydrocortisone in the management of acute hypoadrenocorticism in dogs: a retrospective series of 30 cases. J Small Anim Pract. 2016 May;57(5):227-33. doi: 10.1111/jsap.12473. PubMed PMID: 27101159.

12/02/16 Chu: Acute Tumor Lysis Syndrome; Lymphoproliferative Diseases; Glomerular Disease

Rout ED, Avery PR. Lymphoid Neoplasia: Correlations Between Morphology and Flow Cytometry. Vet Clin North Am Small Anim Pract. 2017 Jan;47(1):53-70. doi:10.1016/j.cvsm.2016.07.004. Review. PubMed PMID: 27542692.

IRIS Canine GN Study Group Diagnosis Subgroup., Littman MP, Daminet S, Grauer GF, Lees GE, van Dongen AM. Consensus recommendations for the diagnostic investigation of dogs with suspected glomerular disease. J Vet Intern Med. 2013 Nov-Dec;27 Suppl 1:S19-26. doi: 10.1111/jvim.12223. PubMed PMID: 24635376.

11/18/16 Reinero: Bacterial Pneumonia

Sumner CM, Rozanski EA, Sharp CR, Shaw SP. The use of deep oral swabs as a surrogate for transoral tracheal wash to obtain bacterial cultures in dogs with pneumonia. J Vet Emerg Crit Care (San Antonio). 2011 Oct;21(5):515-20. doi:
10.1111/j.1476-4431.2011.00670.x. PubMed PMID: 22316198.

Proulx A, Hume DZ, Drobatz KJ, Reineke EL. In vitro bacterial isolate susceptibility to empirically selected antimicrobials in 111 dogs with bacterial pneumonia. J Vet Emerg Crit Care (San Antonio). 2014 Mar-Apr;24(2):194-200. doi: 10.1111/vec.12128. PubMed PMID: 24382329.

11/11/16 Rothacker: Mucopolysaccharidosis

Jolly RD, Hopwood JJ, Marshall NR, Jenkins KS, Thompson DJ, Dittmer KE, Thompson JC, Fedele AO, Raj K, Giger U. Mucopolysaccharidosis type VI in a Miniature Poodle-type dog caused by a deletion in the arylsulphatase B gene. N Z Vet J. 2012 May;60(3):183-8. doi: 10.1080/00480169.2011.642791. PubMed PMID:22329490; PubMed Central PMCID: PMC3401909.

Jolly RD, Johnstone AC, Norman EJ, Hopwood JJ, Walkley SU. Pathology of mucopolysaccharidosis IIIA in Huntaway dogs. Vet Pathol. 2007 Sep;44(5):569-78. PubMed PMID: 17846229.

Skelly BJ, Franklin RJ. Recognition and diagnosis of lysosomal storage diseases in the cat and dog. J Vet Intern Med. 2002 Mar-Apr;16(2):133-41. Review. PubMed PMID: 11899921.

11/04/16 Asokan: Pyothorax

Bach JF, Balakrishnan A. Retrospective comparison of costs between medical and surgical treatment of canine pyothorax. Can Vet J. 2015 Nov;56(11):1140-3. PubMed PMID: 26538667; PubMed Central PMCID: PMC4608465.

Swinbourne F, Baines EA, Baines SJ, Halfacree ZJ. Computed tomographic findings in canine pyothorax and correlation with findings at exploratory thoracotomy. J Small Anim Pract. 2011 Apr;52(4):203-8. doi:10.1111/j.1748-5827.2011.01051.x. PubMed PMID: 21906063.

10/28/16 Trenholme: Septic Peritonitis

Lascelles BD, Blikslager AT, Fox SM, Reece D. Gastrointestinal tract perforation in dogs treated with a selective cyclooxygenase-2 inhibitor: 29 cases (2002-2003). J Am Vet Med Assoc. 2005 Oct 1;227(7):1112-7. PubMed PMID: 16220672.

Ragetly GR, Bennett RA, Ragetly CA. Septic peritonitis: etiology, pathophysiology, and diagnosis. Compend Contin Educ Vet. 2011 Oct;33(10):E1-6; quiz E7. Review. PubMed PMID: 22012841.

Barfield DM, Tivers MS, Holahan M, Welch K, House A, Adamantos SE. Retrospective evaluation of recurrent secondary septic peritonitis in dogs (2000-2011): 41 cases. J Vet Emerg Crit Care (San Antonio). 2016 Mar-Apr;26(2):281-7. doi: 10.1111/vec.12413. PubMed PMID: 26523410.

10/14/16 Mark Harmon: Pulmonary Hypertension

Borgarelli M, Abbott J, Braz-Ruivo L, Chiavegato D, Crosara S, Lamb K, Ljungvall I, Poggi M, Santilli RA, Haggstrom J. Prevalence and prognostic importance of pulmonary hypertension in dogs with myxomatous mitral valve disease. J Vet Intern Med. 2015 Mar-Apr;29(2):569-74. doi: 10.1111/jvim.12564.PubMed PMID: 25818210; PubMed Central PMCID: PMC4895522.

Brown AJ, Davison E, Sleeper MM. Clinical efficacy of sildenafil in treatment of pulmonary arterial hypertension in dogs. J Vet Intern Med. 2010 Jul-Aug;24(4):850-4. doi: 10.1111/j.1939-1676.2010.0517.x. Epub 2010 Apr 16. PubMed PMID: 20412435.

Humbert M, Sitbon O, Simonneau G. Treatment of pulmonary arterial hypertension. N Engl J Med. 2004 Sep 30;351(14):1425-36. Review. PubMed PMID:15459304.

10/07/16 O'Brien: Orofacial Disorders

Pakozdy A, Gruber A, Kneissl S, Leschnik M, Halasz P, Thalhammer JG. Complex partial cluster seizures in cats with orofacial involvement. J Feline Med Surg. 2011 Oct;13(10):687-93. doi: 10.1016/j.jfms.2011.05.014. Epub 2011 Jul 26. PubMed
PMID: 21795088.

Baird JD, Arroyo LG, Vengust M, McGurrin MK, Rodriguez-Palacios A, Kenney DG, Aravagiri M, Maylin GA. Adverse extrapyramidal effects in four horse given fluphenazine decanoate. J Am Vet Med Assoc. 2006 Jul 1;229(1):104-10. PubMed  PMID: 16817724.

09/30/16 Jaffey: Erythrocyte Enzyme Deficiences; Methemoglobinemia

Harvey JW. Pathogenesis, laboratory diagnosis, and clinical implications of erythrocyte enzyme deficiencies in dogs, cats, and horses. Vet Clin Pathol. 2006 Jun;35(2):144-56. Review. PubMed PMID: 16783707.

Wright RO, Lewander WJ, Woolf AD. Methemoglobinemia: etiology, pharmacology, and clinical management. Ann Emerg Med. 1999 Nov;34(5):646-56. Review. PubMed PMID: 10533013.

09/23/16 Mauler: Brain Tumor Treatment; Intracranial Meningiomas

Hu H, Barker A, Harcourt-Brown T, Jeffery N. Systematic Review of Brain Tumor Treatment in Dogs. J Vet Intern Med. 2015 Nov-Dec;29(6):1456-63. doi:10.1111/jvim.13617. Epub 2015 Sep 16. Review. PubMed PMID: 26375164; PubMed
Central PMCID: PMC4895648.

Cameron S, Rishniw M, Miller AD, Sturges B, Dewey CW. Characteristics and Survival of 121 Cats Undergoing Excision of Intracranial Meningiomas (1994-2011). Vet Surg. 2015 Aug;44(6):772-6. doi: 10.1111/vsu.12340. Epub 2015 Jun 1. PubMed
PMID: 26032173.

09/16/16 Kerl: Peritoneal Dialysis

Bersenas AM. A clinical review of peritoneal dialysis. J Vet Emerg Crit Care. 2011 Dec;21(6):605-17. doi: 10.1111/j.1476-4431.2011.00679.x. Epub 2011 Sep 21. Review. PubMed PMID: 22316253.

Ross LA, Labato MA. Peritoneal dialysis In: DiBartola SP (ed.) Fluid, Electrolyte, and Acid-Base Disorders in Small Animal Practice. St. Louis: Elsevier, 2012. pp. 665-679.

De Loor J, Daminet S, Smets P, Maddens B, Meyer E. Urinary biomarkers for acute kidney injury in dogs. J Vet Intern Med. 2013 Sep-Oct;27(5):998-1010. doi: 10.1111/jvim.12155. Epub 2013 Aug 19. Review. PubMed PMID: 23952327. [Note: won't be discussed]

Nielsen LK, Bracker K, Price LL. Administration of fenoldopam in critically ill small animal patients with acute kidney injury: 28 dogs and 34 cats (2008-2012). J Vet Emerg Crit Care. 2015 May-Jun;25(3):396-404. doi: 10.1111/vec.12303. Epub 2015 Apr 8. PubMed PMID: 25854861. [Note: won't be discussed]

09/09/16 Bechtel: Cancer Immunotherapy

Grosenbaugh DA, Leard AT, Bergman PJ, Klein MK, Meleo K, Susaneck S, Hess PR, Jankowski MK, Jones PD, Leibman NF, Johnson MH, Kurzman ID, Wolchok JD. Safety and efficacy of a xenogeneic DNA vaccine encoding for human tyrosinase as adjunctive treatment for oral malignant melanoma in dogs following surgical excision of the primary tumor. Am J Vet Res. 2011 Dec;72(12):1631-8. doi:10.2460/ajvr.72.12.1631. PubMed PMID: 22126691.

Regan D, Guth A, Coy J, Dow S. Cancer immunotherapy in veterinary medicine: Current options and new developments. Vet J. 2016 Jan;207:20-8. doi:10.1016/j.tvjl.2015.10.008. Epub 2015 Oct 13. Review. PubMed PMID: 26545847.